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Monographs & Whitepapers

Advancing Fibromyalgia Management With a Novel Sublingual Formulation of Cyclobenzaprine

This monograph details the clinical efficacy and safety of TNX-102 SL, a sublingual formulation of cyclobenzaprine that targets nonrestorative sleep and modulates centralized pain, as a treatment for fibromyalgia.

AUGUST 6, 2025

Magnetic Peripheral Nerve Stimulation For Chronic Neuropathic Pain: A Review of Recent Evidence

This article explores magnetic peripheral nerve stimulation, a noninvasive approach to pain management supported by emerging evidence in the treatment of neuropathic pain and other conditions.

JUNE 9, 2025

Unraveling Fibromyalgia: Diagnostic Dilemmas and Therapeutic Complexities

This clinical review summarizes challenges related to the diagnosis and management of fibromyalgia, highlighting the limitations of existing diagnostic criteria and current treatment options.

MAY 27, 2025

Managing Lumbar Disc Herniation: Current Treatment Limitations and Economic Burden

This monograph reviews the diagnosis of lumbar disc herniation; available treatment options, including a discussion of limitations in the current treatment landscape; and the associated economic burden and impact on quality of life for affected patients.

MARCH 17, 2025

The NOPAIN Act: Clinical and Financial Opportunities in Hospital Outpatient and Ambulatory Settings

This monograph features the clinical perspectives from those working in the trenches of postsurgical pain management, and addresses how their institutions are preparing for separate Medicare reimbursement for certain branded non-opioid analgesics for procedures in the hospital outpatient and ambulatory settings.

OCTOBER 14, 2024

Robust Evidence for Managing Pain With Nalu Peripheral Nerve Stimulation

This article highlights the Nalu Neurostimulation System in providing a convenient and highly effective solution for the management of chronic neuropathic pain, and reviews recent outcomes and economic benefits supporting its use with conventional medical management in treating chronic peripheral neuropathic pain.

SEPTEMBER 30, 2024

Intravenous Ibuprofen for the Treatment of Pain and Fever: An Update

Intravenous ibuprofen (IVIB; Caldolor®) has been studied extensively in a variety of clinical areas and has emerged as a safe and effective alternative to other nonsteroidal anti-inflammatory drugs. This Special Report evaluates the current data supporting the use of IVIB as a standard of care for the treatment of pain and fever in adult and pediatric patients.

MAY 24, 2024

Emerging Trends in Perioperative Pain Control in Shoulder Surgery

This article is based on a symposium held at the annual meeting of the American Shoulder and Elbow Surgeons, and describes the use of liposomal bupivacaine as part of a multimodal approach to managing surgical pain, while minimizing opioid use and optimizing clinical outcomes in patients undergoing shoulder procedures.

SEPTEMBER 22, 2023

Uncovering the Therapeutic Potential of High Concentration Capsaicin: Use of QUTENZA® (capsaicin) 8% Topical System For Managing Painful Symptoms Associated With Diabetic Peripheral Neuropathy of the Feet

This article is based on a symposium held at the 2023 annual meeting of the American Academy of Pain Medicine, and reviews the development and efficacy of QUTENZA for management of painful diabetic peripheral neuropathy of the feet, a well-known complication of diabetes.

AUGUST 7, 2023

A Celecoxib and Tramadol Hydrochloride Co-crystal Formulation for the Management of Acute Pain

This monograph reviews the updated CDC recommendations on the management of acute pain, highlighting the availability of a celecoxib and tramadol hydrochloride co-crystal (CTC) formulation to address the gap in treating patients with acute pain that is severe enough for opioid therapy. Cases depicting patients experiencing acute pain who are treated with CTC in the office and surgical settings are included to outline the complexities of managing these patients.

JULY 6, 2023

Localized Treatment With the First and Only Extended-Release Corticosteroid for OA Knee Pain

This article is based on a symposium held at the 2022 annual meeting of the American Orthopaedic Society for Sports Medicine, and provides an overview on the use of ZILRETTA (triamcinolone acetonide extended-release injectable suspension) for the management of osteoarthritis knee pain, as well as clinical outcomes data and patient experience to support its use in addressing challenges observed with traditional intra-articular corticosteroids.

After reading the article, visit ZILRETTApro.com for more information.

JANUARY 12, 2023

iovera°: Targeted Cryoneurolysis for OA Knee and Sports Medicine Patients

This article is based on a symposium held at the 2022 annual meeting of the American Orthopaedic Society for Sports Medicine, and describes the iovera° system, and discusses clinical outcomes and reimbursement for using the technology to manage pain associated with knee injury or osteoarthritis in sports medicine patients. 

Review clinical data from total knee arthroplasty and knee osteoarthritis studies.

NOVEMBER 9, 2022

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