Las Vegas—Treatment with pregabalin, a GABAergic anticonvulsant licensed for use for neuropathic pain, reduces bowel-related symptoms in people with irritable bowel syndrome, researchers have found. Although characterized as a pilot trial, the study was randomized, double-blind and placebo-controlled.
“A larger randomized study is needed to confirm efficacy and safety, but pregabalin was well tolerated and there was significant improvement on the primary end point,” said Yuri