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MARCH 17, 2023

Elimination of the USP 1-Hour Rule

A Spike Through the Heart of the Matter


Originally published by our sister publication Anesthesiology News

Richard A. Jaffe, MD, PhD
John G. Brock-Utne, MD, PhD, FCMSA
Department of Anesthesiology, Perioperative and Pain Medicine
Stanford University
Stanford, Calif.

We read with great interest the recent announcement from the U.S. Pharmacopeia (USP) that it has revised its policy regarding what constitutes compounding.1 As a consequence, The Joint Commission (TJC) has revised its guidance regarding the spiking of IV bags. USP is now saying