As a single agent, the largely forgotten opioid analgesic levorphanol has several beneficial mechanisms for treating pain, according to a literature review of the drug dating back to the late 1940s.
“I am excited that this old drug is finally receiving the recognition that it deserves,” said co-author Jeff Gudin, MD, director of pain management and palliative care at Englewood Hospital and Medical Center in New Jersey. “Levorphanol has truly been overlooked by clinicians over