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JUNE 7, 2024

No Improvement in Pain Scores With Nitrous Oxide for CRPS

SAN FRANCISCO—Clinicians looking for pain treatments for patients with complex regional pain syndrome (CRPS) may not find an effective option in nitrous oxide, according to the results of a new study.

Researchers at Cleveland Clinic concluded that compared with a placebo of air and oxygen, two hours of nitrous oxide and oxygen exposure for three sessions did not decrease pain scores or opioid consumption in such patients.

“Treating CRPS is very difficult, and ketamine infusion is one