Although platelet-rich plasma reduces pain in all orthopedic surgeries, there is substantial variation in effectiveness, and the evidence for clinically significant efficacy is limited to a few indications, according to a systematic review and meta-analysis.
“The rapid proliferation of randomized controlled trials’ evidence around platelet-rich plasma has been pretty astounding,” said principal investigator Herman Johal, MD, MPH, FRCSC, a clinical scholar and PhD candidate at