Portland, Ore.— For cancer patients with opioid-induced constipation, with or without active disease, a single dose of subcutaneous methylnaltrexone (Relistor, Salix Pharmaceuticals) was found to be very effective in producing a rescue-free bowel movement within four hours, and similar effectiveness was also seen in patients with other severe illnesses, according to a new study. The research was a post hoc analysis of three randomized trials conducted between 2003 and 2012.
APRIL 27, 2020