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FEBRUARY 5, 2025

Endocannabinoids Show Promise in Blunting Opioid Reward, Preserving Pain Relief

Despite efforts to reduce reliance on opioids as pain relievers, researchers are still seeking viable alternatives, and prescribers continue to use opioids despite their addictive properties.

However, a team of investigators have begun studying the role that endocannabinoids play in addressing opioid addiction by testing the biological impact of increasing endocannabinoids on opioid reward behavior.
“We were able to blunt opioid reward while preserving the analgesic properties of the