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oic

Methylnaltrexone Effective in Treating OIC in Cancer Patients

Patients with OIC achieved rescue-free laxation within 24 hours of initial dose of methylnaltrexone.

DECEMBER 11, 2023

PAMORAs May Be Best Approach to OIC

“OIC is one of the most common and bothersome symptoms of opioid-induced bowel dysfunction,” the ...

DECEMBER 8, 2023

A Call to My Colleagues: Let's Take A Proactive Approach to Treating Opioid-Induced Constipation

This article describes the results of a recent post hoc analysis assessing the safety and efficacy of subcutaneous ...

NOVEMBER 1, 2022

No Clear Link Between Higher Opioid Consumption and OIC

A retrospective study of cancer patients taking opioid analgesics showed a weak association at most between overall ...

NOVEMBER 20, 2019

OIC Drug More Effective, Safer Than Placebo in Noncancer Pain Patients Across Opioid Doses

The opioid-induced constipation drug naldemedine was shown to be safer and more effective than placebo in patients ...

OCTOBER 23, 2019

Assessing the Burden of Opioid-Induced Constipation: In Pursuit of Fast Relief and Minimal Pharmacokinetic Drug–Drug Interactions

This monograph discusses the unmet needs in patients with opioid-induced constipation (OIC) based on the results of ...

SEPTEMBER 27, 2018

FDA Updates Naloxegol Labeling for Opioid-Induced Constipation to Include Prior Cancer Indication

The FDA has updated the indication of naloxegol (Movantik, AstraZeneca) tablets for the treatment of opioid-induced ...

AUGUST 22, 2017

Efficacy of Naloxegol for OIC Not Influenced by Opioid Type, Dose

Naloxegol to treat opioid-induced constipation showed similar efficacy regardless of opioid type or dose, according ...

JUNE 21, 2017

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