Brain recordings in people with chronic pain reveal a signature activity during recurrent and heightened painful episodes that is distinct from response to acute evoked pain, which investigators have declared a biomarker of chronic pain.
Prasad Shirvalkar, MD, PhD, a pain physician in the Department of Anesthesiology and Perioperative Care in the Division of Pain Medicine at the University of California, San Francisco, and colleagues reported their findings from the first-in-human, long-term