A new study indicates that a combination of the drugs celecoxib and tramadol administered as co-crystals (CTC; Seglentis, Kowa) offers better pain management than each drug taken alone or concomitantly.
In a phase 3, randomized, double-blind, active- and placebo-controlled trial (Pain Pract 2022 Jun 10. doi: 10.1111/papr.13136. Online ahead of print), among patients experiencing severe to moderate pain after bunionectomy with osteotomy, those treated with CTC had greater reductions in their Sum