Opioids should not be recommended for acute nonspecific low back pain (LBP) or neck pain, according to a trial published in the Lancet (2023;402[10398]:304-312) that found “no significant difference in pain severity compared to placebo.”
The article presents the first investigator-led, triple-blind study conducted across 157 primary care clinics and hospitals in Sydney and New South Wales, Australia, between February 2016 and March 2022. Eligible participants included those with LBP,