Initiating opioid use disorder (OUD) therapy with extended-release, injectable naltrexone (XR-naltrexone) within five to seven days of a patient’s seeking treatment is more effective than the standard treatment method of starting within 10 to 15 days, but requires closer medical supervision, according to results from a clinical trial supported by the National Institutes of Health’s National Institute on Drug Abuse (NIDA (JAMA Netw Open 2024;7[5]:e249744).
“Time has been an