Las Vegas—Mistakenly taking oral methotrexate daily instead of weekly can be deadly for patients who have rheumatoid arthritis (RA), psoriasis or other autoimmune diseases.
Sound familiar? That’s likely because the Institute for Safe Medication Practices (ISMP) has been reporting the error since 1996. But the mishap continues to occur, and concern about it has intensified with the increasing use of the potent immunosuppressant for more and more indications, often off-label. In 2017,