Although prescribing benzodiazepines concurrently with opioid analgesics has been shown to raise the risk for fatal overdose, new research documents a risk that is four times that of opioids taken alone, and even at low doses. The new study was published online in the British Medical Journal (2015;350:h2698).
Additionally, the authors found a dose-dependent association with overdose risk. This may “help prioritize how we address this risk,” said Roger Chou, MD, professor in the